hrp0086p2-p777 | Pituitary and Neuroendocrinology P2 | ESPE2016

Impaired Growth Hormone Secretion Associated with Large Hypothalamic Hamartoma

Sukarova-Angelovska Elena , Kocova Mirjana , Angelkova Natalija , Joseva Jasminka

Background: Hypothalamic hamartomas (HH) are rare non-progressive brain tumor malformations that occur early during brain development. Most of the cases are sporadic and nonsyndromic. Variation in size and location of the hamartoma within the hypothalamic region is not always associated with the severity of the clinical presentation. A wide range of symptoms could occur - from nonsymptomatic to severely affected cases that include seizures (mostly gelastic), behavioral difficu...